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Tebanicline hydrochloride Size:Contact [email protected] for quotation Solubility: DMSO: 77 mg/mL (185

SKU: 9132975717

4.2
USD100.00 USD139.00

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Description

Solubility: DMSO: 77 mg/mL (185

It can cause the symptoms of diarrhoea and myelosuppression experienced by ~25% of the patients administered irinotecan

Formula: C135H222O116

Shearer BG

4-dimethoxyphenyl)ethyl]amino}-2-[(1

Tebanicline hydrochloride Size:Contact [email protected] for quotation Solubility: DMSO: 77 mg/mL (185Tebanicline hydrochloride (ABT594 hydrochloride) is a nAChR modulator with potent, orally effective analgesic activity. It inhibits the binding of cytisine to 42 neuronal nAChRs with a Ki of 37 pM. Tebanicline is a novel, potent cholinergic nAChR ligand with analgesic properties that shows preferential selectivity for neuronal nAChRs. It inhibits the binding of cytisine to 42 neuronal nAChRs with a Ki of 37 pM. Functionally, tebanicline is an agonist.

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