Oxindole (Indolin-2-one) vinostat) block of L-type Ca2+ channels

block of L-type Ca2+ channels

InChi: InChI=1S/C21H22N2O3/c1-4-14-10-9-13-16-17(14)19(24)18(20(25)22(16)3)21(26)23(5-2)15-11-7-6-8-12-15/h6-13

Tricaprilin (Trioctanoin) is used in study for patients with mild to moderate Alzheimer's disease and has a role as an anticonvulsant and a plant metabolite

and metastatic melanoma cells (SK-MEL-5

causes cell cycle deregulation

Oxindole (Indolin-2-one) vinostat) block of L-type Ca2+ channelsOxindole (Indolin 2 one) is an aromatic heterocyclic building block. 2 indolinone derivatives have become lead compounds in the research of kinase inhibitors. Oxindole (Indolin 2 one) is a bicyclic structure consisting of a benzene ring fused to 2 pyrrolidone. Substituted indolinones can be referred as 'privileged structures' owing to their excellent binding affinity for many receptors and to the number of approved drugs containing this scaffold.