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187:265-272
PubMed Central PMCID: PMC2702280
TG101348 was used at 1 µM in vitro
Kunisada Y
Alda-1 administration leads to a slight increase in gene expression related to neurogenesis (Nog)
SC-26196 - CAS# 218136-59-5 0060 187:265-272SC 26196, CAS No. 218136 59 5, is a D6D inhibitor (IC50 = 0. 2 M in a rat liver microsomal assay) that completely blocks the conversion of linoleic acid to arachidonic acid (AA). SC 26196 inhibited the desaturation of 2 microM [1 14C] 18: 2n 6 by 87 95% in cultured human skin fibroblasts, coronary artery smooth muscle cells, and astrocytes. By contrast, SC 26196 did not affect the conversion of [1 14C]20: 3n 6 to 20: 4 in the fibroblasts,
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