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21(5):377-83
reversible and potent inhibitor of volume-regulated anion channels (VRAC)
6-2-3-8-14(19)20)7-11-16-9-4-1-5-10-16/h19-20H
CAS Number: 623-17-6
303 (20 mg/kg
BMY 7378 Size:Contact [email protected] for quotation 21(5):377-83BMY 7378 is a 2C and 1D adrenergic receptors inhibitor (pKi= 6. 54 and 8. 2, respectively) and a mixed agonist and antagonist for 5 HT1A receptors. Adrenergic 1 and 2 receptors are G protein coupled receptors that are located in CNS and periphery. It plays a role in regulating neurotransmission, smooth muscle contraction and thermogegualtion. 5 HT receptor is a G protein coupled receptor for 5 hydroxytryptamine (serotonin) that found in nerve systems.