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Azvudine 6652N-PEG2-CH2COOH In rat pharmacokinetic studies

SKU: 13300645792

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Description

In rat pharmacokinetic studies

Smiles: CC(C)[C@H]1C(=O)O[C@@H]2CCN3CC=C(COC(=O)[C@](C)(O)[C@]1(C)O)[C@@H]32

2011 Sep 1

Ro 08-2750 (5-10 μM

Smiles: CC1(C)O[C@@H](OC2=CC=C3C(OC(=O)C(NC(=O)C4NC=C(C(=O)NC5C(=O)OC6=C(C=CC(O[C@@H]7OC(C)(C)[C@H](OC)[C@@H](OC(=O)C8=CC=C(C)N8)[C@H]7O)=C6C)C=5O)C=4C)=C3O)=C2C)[C@H](O)[C@H](OC(=O)C2=CC=C(C)N2)[C@H]1OC

Azvudine 6652N-PEG2-CH2COOH In rat pharmacokinetic studiesAzvudine (RO 0622) is a potent nucleoside reverse transcriptase inhibitor (NRTI), with antiviral activity on HIV, HBV and HCV. Azvudine exerts highly potent inhibition on HIV 1 (EC50s ranging from 0. 03 to 6. 92 nM) and HIV 2 (EC50s ranging from 0. 018 to 0. 025 nM). Azvudine inhibits NRTI resistant viral strains. Product information CAS Number: 1011529 10 4 Molecular Weight: 286. 22 Formula: C9H11FN6O4 Chemical Name: 4 amino 1 [(2R,3S,4R,5R) 5 azido

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