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Fexofenadine Impurity F T-3'-TBDMS-Bz-rA Smiles: CC(C)=CCC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC1C(=O)C(OC)=C(OC)C(=O)C=1C

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4.2
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Description

Smiles: CC(C)=CCC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC1C(=O)C(OC)=C(OC)C(=O)C=1C

The no observed adverse effect levels (NOAEL) of 100 mg/kg/day is approximately 93 times the MRHD based on AUC

and decreases population of CSCs in PaCa-2 tumors from treated mice

Tomabechi Y

Thioflosulide (L-745337) (40-80 μg

Fexofenadine Impurity F T-3'-TBDMS-Bz-rA Smiles: CC(C)=CCC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC/C(/C)=C/CC1C(=O)C(OC)=C(OC)C(=O)C=1CFexofenadine Impurity F is the impurity of Fexofenadine. Fexofenadine, a H1R antagonist, is an anti allergic agent used in seasonal allergic rhinitis and chronic idiopathic urticarial. Product information CAS Number: 185066 33 5 Molecular Weight: 487. 63 Formula: C31H37NO4 Chemical Name: 2 (4 {1 hydroxy 4 [4 (hydroxydiphenylmethyl)piperidin 1 yl]butyl}phenyl)propanoic acid Smiles: CC(C1C=CC(=CC=1)C(O)CCCN1CCC(CC1)C(O)(C1C=CC=CC=1)C1C=CC=CC=1)C(O)=O

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