I-OMe-Tyrphostin AG 538 Catalog No.:M25719-C 80 minutes)

80 minutes)

InChiKey: SQOJOAFXDQDRGF-ZMVGXLHTSA-N

brain-penetrant and orally active chaperone-mediated autophagy (CMA) activator with favorable pharmacokinetics

IC50 values for all other kinases are in the μM range (FYN

Smiles: C=C[C@H]1[C@H](O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2OC(=O)C2=C(C=C(O)C=C2O)C2=CC(O)=CC=C2)OC=C2[C@H]1CCOC2=O

I-OMe-Tyrphostin AG 538 Catalog No.:M25719-C 80 minutes)I OMe Tyrphostin AG 538 (I OMe AG 538) is a specific inhibitor of IGF 1R (insulin like growth factor 1 receptor tyrosine kinase). I OMe Tyrphostin AG 538 inhibits IGF 1R mediated signaling and is preferentially cytotoxic to nutrient deprived PANC1 cells. I OMe Tyrphostin AG 538 is an ATP competitive inhibitor of phosphatidylinositol 5 phosphate 4 kinase (PI5P4K), with an IC50 of 1 M. Product information CAS Number: 1094048 77 7 Molecular Weight: 437.