InChi: InChI=1S/C57H101N13O17S/c1-30(2)27-41(48(60)78)67-52(82)39(19-22-46(76)77)64-49(79)35(15-11-13-24-58)62-51(81)38(18-21-45(74)75)65-53(83)40(23-26-88-10)66-56(86)43(29-32(5)6)69-57(87)47(33(7)8)70-54(84)36(16-12-14-25-59)63-55(85)42(28-31(3)4)68-50(80)37(61-34(9)71)17-20-44(72)73/h30-33
Visootsak J
Mice tolerate intraperitoneal dose of SMI-16a is 50 mg/kg daily for 5 days
Hydroxy Itraconazole is an active metabolite of Itraconazole (ITZ)
the effect of Adjudin is tested in a subcutaneous model of lung and prostate cancer
Antitumor agent-23 yl Enzalutamide D6 InChi: InChI=1S/C57H101N13O17S/c1-30(2)27-41(48(60)78)67-52(82)39(19-22-46(76)77)64-49(79)35(15-11-13-24-58)62-51(81)38(18-21-45(74)75)65-53(83)40(23-26-88-10)66-56(86)43(29-32(5)6)69-57(87)47(33(7)8)70-54(84)36(16-12-14-25-59)63-55(85)42(28-31(3)4)68-50(80)37(61-34(9)71)17-20-44(72)73/h30-33Antitumor agent 23 is a potent anti cancer agent with GI50s of 38, 48, 5, 27, 80, and 28 nM for lymphoma cell line GRANTA 519, KARPAS 422, KARPAS 299, RAMOS, DAUDI, and RAJI, respectively. Antitumoral activity. Product information CAS Number: 2355185 12 3 Molecular Weight: 506. 72 Formula: C28H50N4O4 Chemical Name: (3S) 1 [(2S) 4 methyl 1 [(8S) 8 methyl 3 [(pyrrolidin 1 yl)methyl] 1,5 dioxa 9 azaspiro[5. 5]undecan 9 yl] 1 oxopentan 2 yl] 3 (2
