C=CCNC1N=C(N=C(NCC=C)N=1)N1CCN(CC1)C(C1C=CC(F)=CC=1)C1C=CC(F)=CC=1
specific and irreversible inhibitor of Lysine Specific Demethylase-1 (LSD1)
InChiKey: FWWMRDPEXYCBRS-UHFFFAOYSA-N
Ki8751 (5 mg/kg) completely inhibits tumor growth without affecting body weight
It has no effect on a panel of seven other methyltransferases
CM 11 suvastatin D6 Sodium C=CCNC1N=C(N=C(NCC=C)N=1)N1CCN(CC1)C(C1C=CC(F)=CC=1)C1C=CC(F)=CC=1CM11, also known as Homo PROTAC, acts as a potent VHL inhibitor and induces complete depletion of pVHL30. Product information CAS Number: 2244684 49 7 Molecular Weight: 1179. 45 Formula: C58H82N8O14S2 Synonym: Homo PROTAC Homo PROTAC pVHL30 degrader 1 CM11 VHL inhibitor Chemical Name: N1, N20 Bis((S) 1 ((2S, 4R) 4 hydroxy 2 ((4 (4 methylthiazol 5 yl)benzyl)carbamoyl)pyrrolidin 1 yl) 3, 3 dimethyl 1 oxobutan 2 yl) 3, 6, 9, 12, 15, 18